Hybridization in molecular chemistry is a concept that describes the merging of atomic orbitals to create new hybrid orbitals, which can form sigma bonds and accommodate lone pairs of electrons. This process helps explain the geometry of molecular structures and the distribution of electrons around atoms. For instance, in methane (CH4), the carbon atom undergoes sp3 hybridization, resulting in four equivalent orbitals arranged tetrahedrally. Understanding hybridization is crucial for predicting molecular shapes, bond angles, and the overall behavior of molecules. It bridges quantum mechanics with practical chemical bonding, enhancing our ability to manipulate and utilize chemical compounds in various fields like pharmaceuticals and materials science.